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We have to accept that bronchial asthma incorporates a medical phenotype, inflammatory phenotype and remodelling phenotype, and the interactions and contributions from each facet will decide the simplest remedy in the individual patient ( figure 1 ). An instance of using structural airway modifications to determine clusters or phenotypes was undertaken utilizing excessive-resolution CT scans in adults 14 This allowed distinction of patients into clusters according to their bronchial wall volume or bronchial lumen quantity and revealed one particular cluster had very little evidence of bronchial wall changes that might be appropriate with airway remodelling on CT. This is an fascinating finding as it’s normally assumed that every one patients with asthma have airway remodelling.
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